I haven't cloned anything, if I ever get the disk recognised I'll copy the data. The steps I've taken so far are ..
(1) Connected the disk and booted Windows, expecting to see it as unallocated, but instead finding that Windows doesn't see it
(2) Checked it's visible to the BIOS
(3) Disconnected the existing drives, booted off USB and installed Windows onto the 4TB
(4) Shutdown, reconnected the pre-existing drives, reset the boot order in the BIOS, and booted my normal Windows again.
Step 3 was suggested by one of the guys at work firstly to see whether it works, and secondly thinking that possibly once it had been formatted by Windows it might now be visible to my normal Windows.
I have a nasty feeling there is something about which mode the disk or disk controller is set to when Windows is first installed, and a vague memory that this can't be changed without complete reinstallation.